I’m playing XCOM 2 WotC with Mods using Alternative Mod Loader (AML). Is it possible to use mods with WeMod/Wand?
Hello and welcome back to the community. 
Wand does not test its software with third-party software or other mods. There are too many in existence, and there is never any guarantee they are up-to-date. This is something you will need to test for yourself.
While I have not used that specific mod loader, I have used script extender mod loaders on games like Elder Scrolls, Fallout and so on. For those ones, in order to get the Wand (formerly WeMod) to work, the game has to be launched via the mod loader before you press the Play button in Wand (ideally when on the game’s main menu). You can try this for Xcom 2.
Ok, I can test it in that way.