If it uses the same connector, then yes. I said that because i haven’t seen a xbox 360 that uses a pc fan connector. (it’s not like all fans used to cool electronics has the same connector)
And molex should power the fans fine. I have done that multiple times. You will need an external power-source tho. Or you can do what I suggested earlier (replacing the male connector)
If you want to use an external molex then yea you could without any issues. Otherwise you will just solder to the motherboard 12v points.
this is probably irrelevant but why dont you just buy the xtra usb coolers,the plug straight in and away you go.they are keeping my 8yr old system going.or pick up a broken console to rob the fans.sorry if this is totally the wrong direction